Clinical pharmacology and pharmacometrics

Course Duration: 12 weeks
Delivery Mode: Online
Eligibility: Scientists from fields including medicine, pharmacy, statistics, engineering
Course fee: Sponsored by Pharmacometrics Africa

Overview

This online course is part of a set of training activities offered by Pharmacometrics Africa to support the development of pharmacometric competency and expertise in Africa and low and middle income countries.

Pharmacometrics is the science of developing and applying mathematical and statistical models to characterize, understand and predict a drug’s pharmacokinetics, pharmacodynamics and biomarker-outcome behaviour. By using pharmacometrics, researchers can model the characteristics of new drugs to simulate and predict their behaviour, which can then enable more efficient development of new drugs and to improve use of existing drugs.

Course Aim

The overall objective of this course is to foster a pharmacometrics & clinical pharmacology community of practice on the African continent.

Format

The course consists of videos, lectures, internet links, pdf documents as well as discussion fora, quizzes and live tutorials. All participants are assigned into small groups under the mentorship of a member of the course faculty.

Module 1

Clinical Pharmacology and Pharmacometrics

Module 2

Absorption and Distribution

Module 3

Elimination

Module 4

Pharmacokinetics after single dose administration

Module 5

Pharmacology

Module 6

Pharmacometrics at Steady state

Module 7

Fundamentals of biostatistics

Module 8

Modelling in Berkeley Madonna: Introduction and pharmacokinetic models for intravenous administration

Module 9

Modelling in Berkeley Madonna: Pharmacokinetic models for infusion, oral administration, and repeated dosing

Module 10

Modelling in Berkeley Madonna: Linking pharmacokinetic and pharmacodynamic models

Module 11

Data Analysis and Regression

Module 12

Model-independent Analysis and Bioequivalence Assessment


Facilitators
Trainers will include both national and international subject matter experts.

At a glance

Duration
12 weeks

Sessions
12

Discussion forums
Yes

live tutorials
Yes

Quizes
1

Certification
Yes

Pass mark
75%

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